Paraneoplastic pemphigus associated with squamous cell carcinoma of the cervix

Abstract Background Paraneoplastic pemphigus is an autoimmune skin and mucosal disorder, rarely associated with solid malignancies, devastating impact. Patients methods Herein, we report the case of a middle-aged patient who presented recalcitrant stomatitis was ultimately diagnosed advanced-stage cervical cancer. Results Despite prompt initiation immunosuppressive medications, in parallel systemic therapy for her underlying neoplasm, she eventually died within 10 months. Conclusions Considering its heterogeneous clinicopathological immunological manifestations, paraneoplastic remains genuine diagnostic challenge, whereas abysmal prognosis highlights need additional effective immunosuppressants.